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Unfortunately, some dogs just hate car rides, and there is nothing you can do about it. Sometimes cuddling them helps, but if you are the only one in the car then it's not the safest thing to drive while cuddling a dog. The only suggestion I have is benadryl. When we drove 25 hours across the country with our dog, we had him on benadryl the whole time just to calm him down. About 3 hours into our trip, we ran into a little terrier/pomeranian mix at a rest stop. This dog was shaking, not eating, throwing up, and just totally unhappy. We happened to be parked next to them, and the dog's owner was really shaken up about it. Because my boyfriend worked at a vet for two years, he looked at the dog and we gave her some pumpkin to ease her stomach upset, and part of a benadryl to calm her down. I don't know how that dog did the rest of the ride, but hopefully we helped! Poor owner was totally freaked out about her dog's behavior.
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