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Hi umangkej, welcome to the forum!
As a water conditioner, SeaChem Prime only needs to be added during partial water change. If there is an ammonia spike when you already have fish in the aquarium, then partial water change with Prime every other day is a solution to minimize the ammonia damage to the fish.
By the way, do you have fish in your aquarium? Or are you trying to do fishless cycling?
If it is the latter, you need a source of ammonia to get the aquarium nitrogen cycle started. In this case, you do not even need partial water change at all until the nitrate concentration is too high.
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Water conditioner use during fishless nitrogen cycle
