I assume you were referring to glass tanks from the fact you have mentioned temperature and humidity? Will a 3' x 3' x 1' (instead of the 4' x 2' x 1') do for the same 6 feet snake?
From what you said, the reptile community is quite similar to fish keeping community lol. Many people tried to come up with a universal standard, but there is none. While it is extremely important we must have large enough fish tank for fish, there is actually no set to stone rule for fish tank size for fish because many species are too different. We have to use estimation along with common sense.
For the lizards, is there an estimated enclosure size for a certain sized animal?
By the way, is it the bigger the better?