Well, it depends on what you mean by "domesticated". Beyond the common species kept as pets, most species of snakes and lizards are readily available to almost anyone if you know where to look, with the exception of animals listed add CITES appendix 1, (i.e. Komodo dragon, Varanus komodoensis; tuatara, Sphenodon spp.), or animals from a country that had closed its borders on animal trade, (i.e. Australia, madagascar), and there wasn't already a breeding population outside that country. And of course, if you had the money to buy some of the rarer animals.
Other than that, almost everything is available. They all aren't breeding in captivity, as some reptile species are tricky to breed. And, typically, if you are one of a handful of people to breed something, you can pretty much name your price if there is any demand. The next big purchase I want to make is a boelens python, Morelia boeleni. There its a guy who has a clutch of eggs on the ground now. There have been a very limited number of successful begins of these in captivity, 4 or 5 I think. And they are extraordinary serpents. I will have to settle for one the farmed neonates hatched in indonesia and shipped over. And even those are quite expensive.
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